News Release:

March 12, 2007

Singapore - MediPearl Announced Launching of the First Product: Proveq MPCB
 

 
 

MediPearl Pte Ltd announced today the launch of our first product, Proveq MPCB. Proveq MPCB is currently available at the pharmacy of National Cancer Centre and selected specialist clinics and pharmacy outlets.

Proveq MPCB was launched as a Chinese Proprietary Medicine (CPM) in Singapore to improve the lung conditions including lung conditions resulting from smoking. According to the Pharmacopeia of the People’s Republic of China, the herb clears heat, relieves toxicity, clears lungs and resolves phlegm. Traditionally, its main clinical usage is for pulmonary abscess, coughing and improvement of lung conditions including those resulting from chronic smoking. Proveq MPCB has been gone through vigorously animal efficacy tests and animal toxicity studies at MediPearl. No adverse effects have been observed in animals or patients in our daily recommended dosage.

A phase I/II trial on Proveq MPCB was conducted at Department of Medical Oncology, Singapore General Hospital in advanced lung cancer patients who had failed all conventional chemotherapies. Patients were accrued and given Proveq MPCB for 3 months. Proveq MPCB is well tolerated. Patient’s quality of life is improved. Patients responded well and median survival time was extended from the expected 4.5 months to 9.5 months for the entire group.

MediPearl will extend the clinical trial (phase I) to late-stage breast cancer patients soon at National Cancer Centre. MediPearl is also anticipated to have a randomized phase III clinical trial of Proveq MPCB to 120 advanced breast cancer patients in the recurrence of patients with metastasis breast cancer at National Cancer Centre in the last quarter of the year 2007.

“We are very excited about the product, the clinical trial plans of Proveq MPCB and the commercialization initiatives of MediPearl,” stated Mr. C.J. Han, Managing Director of MediPearl. “Our research and development is focusing on creating a diverse phytomedicinal pipeline of high value with large marketing potential and are developing effective and consistent plant-derived products aimed for treatment & prevention of human diseases through evidence-based scientific and clinical studies.”